Thompkin is writing to Crowe to tell him about the area of land he has settled in Liberia, the journey over of which he mentions a small outbreak of smallpox on the ship the Brig Alida, and his family is "injoying good health".
Thompkins (a free man of color) is updating Crowe on his journey through New Orleans to Liberia. He talks about the slaves that he is taking to Liberia.